Gene name:
CHKB (CHETK;CHKL) ;
Protein name:
Choline/ethanolamine kinase ;
Alternative:
Choline kinase-like protein ;2.7.1.32;Choline kinase beta (CK;CKB) ;Ethanolamine kinase beta (EKB) ;2.7.1.82;Ethanolamine kinase (EK) ;choline/ethanolamine kinase beta (CKEKB) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer, and heterodimer with CHKA.
Function:
Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis.
Subcellular Location:
N/A
Protein Attributes:
50:
MAAEATAVAG | SGAVGGCLAK | DGLQQSKCPD | TTPKRRRASS | LSRDAERRAY |
100:
QWCREYLGGA | WRRVQPEELR | VYPVSGGLSN | LLFRCSLPDH | LPSVGEEPRE |
150:
VLLRLYGAIL | QGVDSLVLES | VMFAILAERS | LGPQLYGVFP | EGRLEQYIPS |
200:
RPLKTQELRE | PVLSAAIATK | MAQFHGMEMP | FTKEPHWLFG | TMERYLKQIQ |
250:
DLPPTGLPEM | NLLEMYSLKD | EMGNLRKLLE | STPSPVVFCH | NDIQEGNILL |
300:
LSEPENADSL | MLVDFEYSSY | NYRGFDIGNH | FCEWVYDYTH | EEWPFYKARP |
350:
TDYPTQEQQL | HFIRHYLAEA | KKGETLSQEE | QRKLEEDLLV | EVSRYALASH |
395:
FFWGLWSILQ | ASMSTIEFGY | LDYAQSRFQF | YFQQKGQLTS | VHSSS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Human Choline/ethanolamine kinase
ELISA Kit for Human Choline/ethanolamine kinase
ELISA Kit for Human Choline/ethanolamine kinase
CLIA Kit for Human Choline/ethanolamine kinase
CLIA Kit for Human Choline/ethanolamine kinase
CLIA Kit for Human Choline/ethanolamine kinase
Polyclonal Antibody for Human Choline/ethanolamine kinase
Polyclonal Antibody for Human Choline/ethanolamine kinase
Polyclonal Antibody for Human Choline/ethanolamine kinase
Monoclonal Antibody for Human Choline/ethanolamine kinase
Monoclonal Antibody for Human Choline/ethanolamine kinase
Monoclonal Antibody for Human Choline/ethanolamine kinase
Protein for Human Choline/ethanolamine kinase
Protein for Human Choline/ethanolamine kinase
Protein for Human Choline/ethanolamine kinase
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.
"A genome annotation-driven approach to cloning the human ORFeome."
Collins J.E.
,
Wright C.L.
,
Edwards C.A.
,
Davis M.P.
,
Grinham J.A.
,
Cole C.G.
,
Goward M.E.
,
Aguado B.
,
Mallya M.
,
Mokrab Y.
,
Huckle E.J.
,
Beare D.M.
,
Dunham I.
Genome Biol.5:R84.1-R84.11(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
4.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
,
Suzuki Y.
,
Nishikawa T.
,
Otsuki T.
,
Sugiyama T.
,
Irie R.
,
Wakamatsu A.
,
Hayashi K.
,
Sato H.
,
Nagai K.
,
Kimura K.
,
Makita H.
,
Sekine M.
,
Obayashi M.
,
Nishi T.
,
Shibahara T.
,
Tanaka T.
,
Ishii S.
,
Yamamoto J.
,
Saito K.
,
Kawai Y.
,
Isono Y.
,
Nakamura Y.
,
Nagahari K.
,
Murakami K.
,
Yasuda T.
,
Iwayanagi T.
,
Wagatsuma M.
,
Shiratori A.
,
Sudo H.
,
Hosoiri T.
,
Kaku Y.
,
Kodaira H.
,
Kondo H.
,
Sugawara M.
,
Takahashi M.
,
Kanda K.
,
Yokoi T.
,
Furuya T.
,
Kikkawa E.
,
Omura Y.
,
Abe K.
,
Kamihara K.
,
Katsuta N.
,
Sato K.
,
Tanikawa M.
,
Yamazaki M.
,
Ninomiya K.
,
Ishibashi T.
,
Yamashita H.
,
Murakawa K.
,
Fujimori K.
,
Tanai H.
,
Kimata M.
,
Watanabe M.
,
Hiraoka S.
,
Chiba Y.
,
Ishida S.
,
Ono Y.
,
Takiguchi S.
,
Watanabe S.
,
Yosida M.
,
Hotuta T.
,
Kusano J.
,
Kanehori K.
,
Takahashi-Fujii A.
,
Hara H.
,
Tanase T.-O.
,
Nomura Y.
,
Togiya S.
,
Komai F.
,
Hara R.
,
Takeuchi K.
,
Arita M.
,
Imose N.
,
Musashino K.
,
Yuuki H.
,
Oshima A.
,
Sasaki N.
,
Aotsuka S.
,
Yoshikawa Y.
,
Matsunawa H.
,
Ichihara T.
,
Shiohata N.
,
Sano S.
,
Moriya S.
,
Momiyama H.
,
Satoh N.
,
Takami S.
,
Terashima Y.
,
Suzuki O.
,
Nakagawa S.
,
Senoh A.
,
Mizoguchi H.
,
Goto Y.
,
Shimizu F.
,
Wakebe H.
,
Hishigaki H.
,
Watanabe T.
,
Sugiyama A.
,
Takemoto M.
,
Kawakami B.
,
Yamazaki M.
,
Watanabe K.
,
Kumagai A.
,
Itakura S.
,
Fukuzumi Y.
,
Fujimori Y.
,
Komiyama M.
,
Tashiro H.
,
Tanigami A.
,
Fujiwara T.
,
Ono T.
,
Yamada K.
,
Fujii Y.
,
Ozaki K.
,
Hirao M.
,
Ohmori Y.
,
Kawabata A.
,
Hikiji T.
,
Kobatake N.
,
Inagaki H.
,
Ikema Y.
,
Okamoto S.
,
Okitani R.
,
Kawakami T.
,
Noguchi S.
,
Itoh T.
,
Shigeta K.
,
Senba T.
,
Matsumura K.
,
Nakajima Y.
,
Mizuno T.
,
Morinaga M.
,
Sasaki M.
,
Togashi T.
,
Oyama M.
,
Hata H.
,
Watanabe M.
,
Komatsu T.
,
Mizushima-Sugano J.
,
Satoh T.
,
Shirai Y.
,
Takahashi Y.
,
Nakagawa K.
,
Okumura K.
,
Nagase T.
,
Nomura N.
,
Kikuchi H.
,
Masuho Y.
,
Yamashita R.
,
Nakai K.
,
Yada T.
,
Nakamura Y.
,
Ohara O.
,
Isogai T.
,
Sugano S.
more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
5.
"The DNA sequence of human chromosome 22."
Dunham I.
,
Hunt A.R.
,
Collins J.E.
,
Bruskiewich R.
,
Beare D.M.
,
Clamp M.
,
Smink L.J.
,
Ainscough R.
,
Almeida J.P.
,
Babbage A.K.
,
Bagguley C.
,
Bailey J.
,
Barlow K.F.
,
Bates K.N.
,
Beasley O.P.
,
Bird C.P.
,
Blakey S.E.
,
Bridgeman A.M.
,
Buck D.
,
Burgess J.
,
Burrill W.D.
,
Burton J.
,
Carder C.
,
Carter N.P.
,
Chen Y.
,
Clark G.
,
Clegg S.M.
,
Cobley V.E.
,
Cole C.G.
,
Collier R.E.
,
Connor R.
,
Conroy D.
,
Corby N.R.
,
Coville G.J.
,
Cox A.V.
,
Davis J.
,
Dawson E.
,
Dhami P.D.
,
Dockree C.
,
Dodsworth S.J.
,
Durbin R.M.
,
Ellington A.G.
,
Evans K.L.
,
Fey J.M.
,
Fleming K.
,
French L.
,
Garner A.A.
,
Gilbert J.G.R.
,
Goward M.E.
,
Grafham D.V.
,
Griffiths M.N.D.
,
Hall C.
,
Hall R.E.
,
Hall-Tamlyn G.
,
Heathcott R.W.
,
Ho S.
,
Holmes S.
,
Hunt S.E.
,
Jones M.C.
,
Kershaw J.
,
Kimberley A.M.
,
King A.
,
Laird G.K.
,
Langford C.F.
,
Leversha M.A.
,
Lloyd C.
,
Lloyd D.M.
,
Martyn I.D.
,
Mashreghi-Mohammadi M.
,
Matthews L.H.
,
Mccann O.T.
,
Mcclay J.
,
Mclaren S.
,
McMurray A.A.
,
Milne S.A.
,
Mortimore B.J.
,
Odell C.N.
,
Pavitt R.
,
Pearce A.V.
,
Pearson D.
,
Phillimore B.J.C.T.
,
Phillips S.H.
,
Plumb R.W.
,
Ramsay H.
,
Ramsey Y.
,
Rogers L.
,
Ross M.T.
,
Scott C.E.
,
Sehra H.K.
,
Skuce C.D.
,
Smalley S.
,
Smith M.L.
,
Soderlund C.
,
Spragon L.
,
Steward C.A.
,
Sulston J.E.
,
Swann R.M.
,
Vaudin M.
,
Wall M.
,
Wallis J.M.
,
Whiteley M.N.
,
Willey D.L.
,
Williams L.
,
Williams S.A.
,
Williamson H.
,
Wilmer T.E.
,
Wilming L.
,
Wright C.L.
,
Hubbard T.
,
Bentley D.R.
,
Beck S.
,
Rogers J.
,
Shimizu N.
,
Minoshima S.
,
Kawasaki K.
,
Sasaki T.
,
Asakawa S.
,
Kudoh J.
,
Shintani A.
,
Shibuya K.
,
Yoshizaki Y.
,
Aoki N.
,
Mitsuyama S.
,
Roe B.A.
,
Chen F.
,
Chu L.
,
Crabtree J.
,
Deschamps S.
,
Do A.
,
Do T.
,
Dorman A.
,
Fang F.
,
Fu Y.
,
Hu P.
,
Hua A.
,
Kenton S.
,
Lai H.
,
Lao H.I.
,
Lewis J.
,
Lewis S.
,
Lin S.-P.
,
Loh P.
,
Malaj E.
,
Nguyen T.
,
Pan H.
,
Phan S.
,
Qi S.
,
Qian Y.
,
Ray L.
,
Ren Q.
,
Shaull S.
,
Sloan D.
,
Song L.
,
Wang Q.
,
Wang Y.
,
Wang Z.
,
White J.
,
Willingham D.
,
Wu H.
,
Yao Z.
,
Zhan M.
,
Zhang G.
,
Chissoe S.
,
Murray J.
,
Miller N.
,
Minx P.
,
Fulton R.
,
Johnson D.
,
Bemis G.
,
Bentley D.
,
Bradshaw H.
,
Bourne S.
,
Cordes M.
,
Du Z.
,
Fulton L.
,
Goela D.
,
Graves T.
,
Hawkins J.
,
Hinds K.
,
Kemp K.
,
Latreille P.
,
Layman D.
,
Ozersky P.
,
Rohlfing T.
,
Scheet P.
,
Walker C.
,
Wamsley A.
,
Wohldmann P.
,
Pepin K.
,
Nelson J.
,
Korf I.
,
Bedell J.A.
,
Hillier L.W.
,
Mardis E.
,
Waterston R.
,
Wilson R.
,
Emanuel B.S.
,
Shaikh T.
,
Kurahashi H.
,
Saitta S.
,
Budarf M.L.
,
McDermid H.E.
,
Johnson A.
,
Wong A.C.C.
,
Morrow B.E.
,
Edelmann L.
,
Kim U.J.
,
Shizuya H.
,
Simon M.I.
,
Dumanski J.P.
,
Peyrard M.
,
Kedra D.
,
Seroussi E.
,
Fransson I.
,
Tapia I.
,
Bruder C.E.
,
O'Brien K.P.
,
Wilkinson P.
,
Bodenteich A.
,
Hartman K.
,
Hu X.
,
Khan A.S.
,
Lane L.
,
Tilahun Y.
,
Wright H.
more...
Nature402:489-495(1999)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
Mural R.J.
,
Istrail S.
,
Sutton G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
tissue :
Lung .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-19;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
T-cell .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
"Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide."
Structural genomics consortium (SGC)
Submitted (2009-09) to the PDB data bank
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.3 ANGSTROMS) OF 14-395 IN COMPLEX WITH ADP; MAGNESIUM IONS AND HEMICHOLINIUM-3